4-Ethynylaniline

Product Name	4-Ethynylaniline (Synonyms: 4-Aminophenylacetylene; 1-Amino-4-ethynylbenzene)
CAS NO.	14235-81-5
Formula & Weight	C8H7N (MW: 117.15)
Chemical Structure
Technical Specifications	Appearance: Yellow to brown crystalline powder Purity (HPLC): ≥ 99.0% Melting Point: 98 - 102 °C (Decomposition) Water Content: ≤ 2.0%
Impurity Control
Iron (Fe): ≤ 100 ppm	Sodium (Na): ≤ 150 ppm
Turbidity: ≤ 40 NTU	Absorbance (Vis 450nm): ≤ 1.5

*Strict metal ion control ensures stability in catalytic reactions and polymer curing.

High-Value Applications

4-Ethynylaniline is a versatile alkyne-functionalized building block:

Pharmaceutical Intermediates (Oncology):
A key starting material for the synthesis of Erlotinib Hydrochloride (Tarceva), an EGFR inhibitor used to treat non-small cell lung cancer and pancreatic cancer.
Aerospace Materials (Polyimides):
Used as a reactive End-Capping Agent for high-temperature polyimide resins (e.g., PETI series). It undergoes thermal cross-linking to improve heat resistance and mechanical strength in aerospace composites.

Storage & Handling

Storage: Keep in a cold (2-8°C recommended), dry place. Protect from light and heat to prevent polymerization.

Stability: Contains terminal alkyne group; sensitive to elevated temperatures.

Royalchem guarantees Low Metal Content and High Purity for your sensitive synthesis.

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