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Product Name | Trifluoroacetic acid (TFA) | ||||
CAS NO | 76-05-1 | ||||
Molecular Formula | CF3COOH | ||||
Structural Formula | |||||
Item | Standard | ||||
Appearance | Colorless liquid with a pungent odor | ||||
Molecular Weight | 114.023 | ||||
Trifluoroacetic acid content | ≥99.5% (Actual: 99.96%) | ||||
Boiling Point (1013 hPa) | 72 °C | ||||
Hydrochloric acid (HCl) | ≤0.10% (Actual: 0.018%) | ||||
Sulfuric acid (H2SO4) | ≤0.10% (Actual: 0.009%) | ||||
Hydrofluoric acid (HF) | ≤0.01% (Actual: 0.005%) | ||||
Water content | ≤0.10% (Actual: 0.08%) | ||||
Application | Trifluoroacetic acid (TFA) is extensively applied in organic synthesis, pharmaceuticals, pesticide production, and the electronics sector. It is frequently used as a reagent, solvent, and catalyst in organic synthesis. Specific Applications Include: Peptide Synthesis: TFA is a potent acid that plays a crucial role in solid-phase peptide synthesis by cleaving protective groups from peptide chains. Due to its volatility, it can be easily removed from reaction mixtures, making it an optimal reagent for peptide synthesis. NMR Chemical Shift Reference Compound: TFA is a reference compound for chemical shifts in nuclear magnetic resonance (NMR) spectroscopy. Additional Uses: TFA is also involved in synthesizing other fluorinated compounds and acts as a solvent in various chemical processes. |
Product Name | Trifluoroacetic acid (TFA) | ||||
CAS NO | 76-05-1 | ||||
Molecular Formula | CF3COOH | ||||
Structural Formula | |||||
Item | Standard | ||||
Appearance | Colorless liquid with a pungent odor | ||||
Molecular Weight | 114.023 | ||||
Trifluoroacetic acid content | ≥99.5% (Actual: 99.96%) | ||||
Boiling Point (1013 hPa) | 72 °C | ||||
Hydrochloric acid (HCl) | ≤0.10% (Actual: 0.018%) | ||||
Sulfuric acid (H2SO4) | ≤0.10% (Actual: 0.009%) | ||||
Hydrofluoric acid (HF) | ≤0.01% (Actual: 0.005%) | ||||
Water content | ≤0.10% (Actual: 0.08%) | ||||
Application | Trifluoroacetic acid (TFA) is extensively applied in organic synthesis, pharmaceuticals, pesticide production, and the electronics sector. It is frequently used as a reagent, solvent, and catalyst in organic synthesis. Specific Applications Include: Peptide Synthesis: TFA is a potent acid that plays a crucial role in solid-phase peptide synthesis by cleaving protective groups from peptide chains. Due to its volatility, it can be easily removed from reaction mixtures, making it an optimal reagent for peptide synthesis. NMR Chemical Shift Reference Compound: TFA is a reference compound for chemical shifts in nuclear magnetic resonance (NMR) spectroscopy. Additional Uses: TFA is also involved in synthesizing other fluorinated compounds and acts as a solvent in various chemical processes. |
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