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Cyanamide

CAS NO. 420-04-2
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  • 50% Aqueous Solution / Crystal Grade

  • Royalchem

  • 420-04-2

Product Name Cyanamide
(Synonyms: Hydrogen Cyanamide; Carbamonitrile; Cyanoamine)
CAS NO. 420-04-2
Formula & Molecular Weight CH2N2 (MW: 42.04)
Chemical Structure Cyanamide Hydrogen Cyanamide molecular structure CAS 420-04-2
Product Positioning NCN Building Block / Pharmaceutical Intermediate / Agrochemical Intermediate
Cyanamide is a small but highly reactive nitrogen-containing molecule capable of participating in nucleophilic and electrophilic chemistry. It is widely used as an upstream building block in pharmaceutical, agrochemical and fine chemical synthesis.

Cyanamide Grades Available from Royalchem

Item 50% Aqueous Solution Crystal Grade
Product Form Stabilized aqueous solution Stabilized crystalline / solid Cyanamide
Cyanamide Assay Target concentration around 50%; actual specification subject to current COA High-assay grade; actual specification subject to current COA
Key Quality Parameters Assay, Dicyandiamide, stabilizer and other process-sensitive impurities Assay, Dicyandiamide, water, stabilizer and other process-sensitive impurities
Typical Process Consideration Suitable for processes that can accommodate aqueous feed Useful when higher active content or lower introduced water is preferred
Final Acceptance The applicable supplier specification and actual batch COA prevail.
Why does Dicyandiamide (DCD) matter in Cyanamide?

Cyanamide can undergo dimerization to form Dicyandiamide, particularly under unfavorable chemical or storage conditions. For this reason, DCD is an important quality parameter when evaluating Cyanamide for process-sensitive applications. Customers should specify their required DCD limit when requesting a quotation.

Cyanamide Stability: Why Stabilizer, pH and Storage Matter

Dimerization Cyanamide can dimerize to Dicyandiamide under alkaline conditions.
Hydration Under unsuitable acidic conditions, hydration reactions can lead toward urea formation.
Stabilizer Commercial Cyanamide grades are therefore commonly stabilized. Stabilizer type and level should be considered when matching a grade to a downstream process.
Storage Storage conditions are grade-specific. Keep containers tightly closed and follow the temperature, compatibility and handling requirements stated in the SDS applicable to the supplied commercial grade.

Key Applications of Cyanamide

Pharmaceutical Synthesis Cyanamide is used as an NCN building block in pharmaceutical synthesis. Current industrial application references associate Cyanamide chemistry with products such as Albendazole, Fenbendazole and Imatinib.
Agrochemical Synthesis Cyanamide is used in the synthesis of nitrogen-containing crop-protection intermediates. Industry application references include chemistry associated with Amitrole, Pyrimethanil and Sulfoxaflor.
Creatine & Creatine Monohydrate A well-established industrial route produces Creatine or Creatine Monohydrate by reacting Cyanamide with sodium or potassium sarcosinate. For this application, Cyanamide assay, DCD, stabilizer and other impurities may influence downstream process and purification requirements.
Guanidine & NCN Chemistry The difunctional nature of Cyanamide makes it a useful precursor for guanidine-related compounds, nitrogen-rich intermediates and heterocyclic chemistry.
Plant Growth Regulator Active Ingredient Hydrogen Cyanamide is used as the active ingredient in registered plant growth regulator products in certain markets for dormancy management and more uniform bud break in crops such as grapes, kiwifruit and orchard crops. Agricultural use is registration- and label-specific.

Cyanamide 50% Solution or Crystal Grade: Which Should You Choose?

Your process can accept water A 50% aqueous Cyanamide solution may be convenient for liquid metering and aqueous-process feeding.
Your process is sensitive to introduced water Crystal grade may be evaluated when higher active content or lower introduced water is preferred. Actual water and stabilizer specifications should still be confirmed.
You already have a target COA Send the target assay, DCD, water, stabilizer and other critical impurity limits to Royalchem for specification matching.

Sourcing Cyanamide / Hydrogen Cyanamide?

Royalchem suppliesCyanamide (Hydrogen Cyanamide, CAS 420-04-2)in50% aqueous solution and crystal gradesfor pharmaceutical, agrochemical, Creatine and fine chemical synthesis.

For faster specification matching, please provide:product form, target assay, Dicyandiamide limit, stabilizer requirement, water / impurity limits, quantity, end use and destination country.

Royalchem can confirmbatch COA, SDS, applicable specification and logistics requirementsfor the actual commercial supply grade.

Cyanamide vs Dicyandiamide vs Calcium Cyanamide

Product Identity Key Difference
Cyanamide CAS 420-04-2 / CH2N2 Reactive NCN building block supplied as stabilized solution or crystal grade.
Dicyandiamide CAS 461-58-5 A different NCN compound and a potential dimerization product of Cyanamide; also a separate commercial chemical.
Calcium Cyanamide Separate calcium-containing compound Not the same substance as Cyanamide / Hydrogen Cyanamide. Always verify the CAS number before sourcing.

Frequently Asked Questions

What is Cyanamide? Cyanamide is a reactive nitrogen-containing compound with CAS 420-04-2 and molecular formula CH2N2. It is widely used as an upstream building block in pharmaceutical, agrochemical and fine chemical synthesis.
Are Cyanamide and Hydrogen Cyanamide the same compound? Yes. In commercial and technical use, Cyanamide and Hydrogen Cyanamide commonly refer to the same substance with CAS 420-04-2.
What is the difference between Cyanamide 50% solution and crystal grade? The main differences are active Cyanamide concentration, introduced water, stabilizer system and impurity profile. Grade selection should be based on the customer's reaction system and target specification.
Why is Dicyandiamide controlled in Cyanamide? Cyanamide can dimerize to form Dicyandiamide. DCD therefore serves as an important quality parameter and may affect downstream reaction and purification requirements.
Why is Cyanamide stabilized? Cyanamide is chemically reactive and can undergo degradation or self-reaction under unsuitable conditions. Commercial grades are commonly stabilized to improve product stability during storage and handling.
How is Cyanamide used in Creatine synthesis? A documented industrial route reacts Cyanamide with sodium or potassium sarcosinate to produce Creatine or Creatine Monohydrate.
What pharmaceutical applications use Cyanamide? Cyanamide is used as a nitrogen-containing building block in pharmaceutical synthesis. Current industry application references include Albendazole, Fenbendazole and Imatinib chemistry.
What agrochemical applications use Cyanamide? Cyanamide is used as a building block in crop-protection chemistry. Current industry application references include Amitrole, Pyrimethanil and Sulfoxaflor.
Is Hydrogen Cyanamide a plant growth regulator? Hydrogen Cyanamide is used as the active ingredient in registered plant growth regulator products in certain markets. Registration, crop use, application timing and dosage are jurisdiction-specific.
Can industrial Cyanamide be applied directly to grapes or kiwifruit? Industrial Cyanamide raw material should not automatically be treated as a registered agricultural product. Agricultural use must follow the registration and approved label requirements applicable in the destination market.
Does Cyanamide require cold-chain shipping? Temperature and transport requirements depend on the commercial grade, stabilizer system, route and applicable SDS. Royalchem does not apply one universal cold-chain statement to every Cyanamide grade; logistics requirements should be confirmed for the actual shipment.
Is Cyanamide non-toxic? No. Cyanamide is a hazardous chemical and requires appropriate engineering controls, personal protective equipment and SDS-based handling procedures.
What information should I provide when requesting a Cyanamide quotation? Please specify product form, target assay, Dicyandiamide limit, stabilizer requirement, water or other critical impurities, quantity, end use and destination country.
Can Royalchem provide COA and SDS? Batch-specific COA, SDS and specification information can be confirmed according to the actual commercial supply source and grade.

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