2,2-Dimethoxypropane

CAS NO. 77-76-9

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Parameter	Specification & Details
Product Name	2,2-Dimethoxypropane (DMP) Synonyms: Acetone dimethyl acetal
CAS Number	77-76-9
Molecular Data	Formula: C₅H₁₂O₂ Weight: 104.15 g/mol
Chemical Structure
Purity (GC)	≥ 99.5% (Pharma Grade)
Moisture Content	≤ 0.1%
Physical Properties	Appearance: Clear colorless liquid Density: 0.847 g/mL at 25°C Boiling Point: 83°C Flash Point: -10°C (Highly Flammable)
Key Applications	DMP serves as a highly efficient moisture scavenger (dehydrating agent) in water-sensitive chemical reactions by reacting with water to form acetone and methanol. It acts as a crucial protecting group for 1,2-diols and 1,3-diols during the synthesis of complex pharmaceutical intermediates, including steroids and antibiotics.
Packaging & Storage	Available in teel Drums or ISO Tanks for bulk transport. Store in a cool, dry, well-ventilated area away from moisture and ignition sources. Shelf life is 24 months under nitrogen blanketing.

Require a Dehydrating Agent for Synthesis?

Royalchem's 2,2-Dimethoxypropane offers Low Moisture Content to maximize your reaction yield.
We ensure safe, compliant delivery to European ports via ISO Tank or Drum.

Industrial Applications of 2,2-Dimethoxypropane (DMP)

2,2-Dimethoxypropane (DMP) is a pharmaceutical-grade reagent widely recognized as a superior hydroxyl protecting agent and dehydrating agent in advanced chemical synthesis. Its exceptional performance surpasses traditional reagents like thionyl chloride and p-methoxybenzaldehyde, making it indispensable for high-quality pharmaceutical manufacturing and fine chemical production across global markets.

• Pharmaceutical Synthesis & Antibiotic Production

Key hydroxyl protecting agent in semisynthetic antibiotic processes, enabling selective protection of sensitive functional groups during multi-step synthesis. Essential for producing high-quality antibiotics with superior therapeutic efficacy and minimal side effects.

Productos finales: β-lactam antibiotics, penicillin derivatives, cephalosporin intermediates, advanced antibiotic formulations

• Vitamin & Nutraceutical Manufacturing

Critical intermediate in the synthesis of fat-soluble vitamins and carotenoids. Provides reliable protection during complex vitamin synthesis processes, ensuring high-purity end products for pharmaceutical and nutritional applications.

Productos finales: Vitamin E (tocopherols), Vitamin A (retinol), astaxanthin, β-carotene, lutein, zeaxanthin

• Fine Chemical & Organic Synthesis

Versatile protecting agent for alcohols and diols in advanced organic synthesis. Functions as an efficient water scavenger in moisture-sensitive reactions, facilitating acetonide formation and selective protection strategies.

Productos finales: Protected alcohols, acetonide derivatives, pharmaceutical intermediates, specialty chemicals, research compounds

• Agrochemical & Pesticide Production

Protecting agent in the synthesis of modern pesticides and agricultural chemicals. Enables selective transformations required for complex agrochemical active ingredients while maintaining product stability and efficacy.

Productos finales: Herbicide intermediates, fungicide compounds, insecticide active ingredients, plant growth regulators

Competitive Advantage: Our pharmaceutical-grade DMP offers superior selectivity, mild reaction conditions, and cost-effectiveness compared to imported alternatives. With consistent high purity (≥99%) and reliable supply chain, we enable European manufacturers to achieve optimal production efficiency while maintaining the highest quality standards.