2-Butene-1,4-diol

CAS NO. 6117-80-2

Availability:

Quantity:



Inquire Add to Basket PDF Export

Product Description

Product Name	(Z)-2-Butene-1,4-diol (Synonyms: cis-2-Butene-1,4-diol; 1,4-Butenediol; cis-1,4-Dihydroxy-2-butene)
CAS NO.	6117-80-2
Formula & Weight	C₄H₈O₂ (MW: 88.11) \| EINECS: 228-085-1
Chemical Structure
Quality Specifications	Appearance: Clear, colorless to light yellow viscous liquid Assay (1,4-Butenediol): ≥ 99.0% 1,4-Butanediol: ≤ 0.60% 1,4-Butynediol: ≤ 0.20% Cis Content: ≥ 97.0% Trans Content: ≤ 2.5% Water Content: ≤ 0.3%
Physical Properties	Density (20°C): 1.072 g/cm³ Boiling Point: 235 ℃ Melting Point: 4 ~ 10 ℃ Flash Point: 127 ℃ (closed cup) Solubility: Very soluble in water, ethanol, acetone
Key Applications	(Z)-2-Butene-1,4-diol is a versatile C4 unsaturated diol widely used in: Vitamin B6 Synthesis: Essential raw material for industrial Pyridoxine/Pyridoxine HCl production via the Diels-Alder cycloaddition route. Pharmaceutical Intermediate: Synthesis of antiviral agents (Oxetanocin A), antibiotics, and MRI contrast agent standards (Gadobutrol impurity). Agrochemical Intermediate: Precursor for crop protection agents and pesticide intermediates. Polymer & Resin Chemistry: Crosslinking agent for alkyd and synthetic resins; monomer for biodegradable polycarbonates.
Packaging & Storage	Packaging: ISO Tank (25,000 kg/tank) / IBC (1,000 kg) / Drum (200 kg). Storage: Store in a cool, dry, well-ventilated place. Keep container tightly closed. Transport: Non-dangerous goods (ADR/RID, IMDG, IATA).

Source High-Purity Butenediol Directly from Royalchem

Royalchem supplies industrial-grade (Z)-2-Butene-1,4-diol with ≥ 99.0% purity and ≥ 97% cis content, trusted by leading global vitamin and pharmaceutical manufacturers. We support bulk ISO Tank shipments (CIF/FOB) to Europe, North America, and worldwide.
Contact us for the latest COA, SDS, and competitive bulk pricing.

Industrial Applications of (Z)-2-Butene-1,4-Diol

Vitamin B6 (Pyridoxine) Synthesis	The primary global application. cis-Butenediol undergoes Diels-Alder cycloaddition in the industrial oxazole route to construct the pyridine ring for Pyridoxine HCl. China produces over 80% of global Vitamin B6, and high-purity BED (≥99%, ≥97% cis) is a critical starting material for major VB6 producers including DSM, Tianxin, Xinfa, Huazhong, and NHU.
Pharmaceutical Intermediates	Chiral building block for benzoxazinyl-oxazolidinone antibacterial agents; precursor for AMF-26 (antitumor, Golgi inhibition); antiviral agent Oxetanocin A synthesis; reference standard impurity for Gadobutrol (MRI contrast agent) quality control.
Agrochemical Intermediates	Precursor for crop protection agent synthesis. Historical use in endosulfan production (phased out under Stockholm Convention); current focus on next-generation pesticide intermediates and agrochemical building blocks.
Polymer & Specialty Chemistry	Crosslinking agent for alkyd and synthetic resins; comonomer with TDI for polyurethane coatings & foams; monomer for biodegradable polycarbonates & polyesters. Also used in plasticizer production, chrome tanning baths, bactericide formulation, and as an intermediate for 1,4-butanediol, lithium battery additives, and LCD materials.

Packaging, Storage & Shipping

Storage	Below 40°C, cool, dry, well-ventilated area. Containers tightly sealed. Protect from direct sunlight. Shelf life: 12 months from manufacture.
Trade Terms	FOB / CIF / CFR. Ports: Shanghai, Nanjing, Ningbo. Lead time: 2–3 weeks (stock items).
Transport Class	Non-dangerous goods — no UN number, no hazmat surcharges (ADR/IMDG/IATA exempt).

Frequently Asked Questions

What is the difference between CAS 6117-80-2 and CAS 110-64-5?	CAS 6117-80-2 is the (Z)-isomer (cis) with ≥97% cis content — the preferred grade for Vitamin B6 synthesis and pharmaceutical use. CAS 110-64-5 is the cis/trans mixture. The cis isomer is more reactive in Diels-Alder reactions. Royalchem supplies CAS 6117-80-2 grade.
What purity is required for Vitamin B6 production?	Major VB6 manufacturers require ≥99.0% assay, ≥97.0% cis, with 1,4-butanediol ≤0.60%, 2-butyn-1,4-diol ≤0.20%, colour ≤100 APHA, moisture ≤0.3%. Royalchem's product meets or exceeds all these parameters.
Is it classified as dangerous goods?	No. Non-dangerous goods under ADR/RID, IMDG, and IATA. No UN number assigned. Ships via standard ocean freight without special permits or hazmat surcharges.
Can you provide COA, SDS, and regulatory documents?	Yes. Every shipment includes a batch-specific COA. SDS/MSDS available in multiple languages. REACH (EU) and TSCA (US) compliance support provided. Sample documents available before purchase.