Fluorocytosine

CAS NO. 2022-85-7

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Product Description

Product Name	Fluorocytosine (Flucytosine) (5-Fluorocytosine / 5-FC / 4-Amino-5-fluoro-2-hydroxypyrimidine)
CAS NO.	2022-85-7
Formula & Weight	C4H4FN3O (MW: 129.09)
Chemical Structure
Specification (EP/USP)	Appearance: White to off-white crystalline powder Assay (On Dried Basis): ≥ 99.50% Loss on Drying: ≤ 1.5% Residue on Ignition: ≤ 0.1% Heavy Metals: ≤ 20ppm Impurity Profile (High Purity): Cytosine: ≤ 0.02% (Limit is far below pharmacopeia specs) 5-Fluorouracil (5-FU): ≤ 0.01% Total Impurities: ≤ 0.03%
Clinical Applications	A potent fluorinated pyrimidine antifungal API, widely used in combination therapies: Systemic Infections: Highly effective against systemic candidiasis and cryptococcosis (e.g., Cryptococcus neoformans meningitis). Synergistic Therapy: Often formulated or co-administered with Amphotericin B for enhanced efficacy. Dermatomycosis: Effective against chromoblastomycosis caused by sensitive strains of Phialophora and Cladosporium species.
Packaging & Storage	Packaging: 25kg Cardboard Drum with double PE liners. Storage: Preserve in tight, light-resistant containers. Store at controlled room temperature (avoid excessive heat).

Need High Purity 5-FC for Formulation?

Royalchem supplies Pharmaceutical Grade Fluorocytosine with industry-leading impurity control (5-FU ≤ 0.01%).
Reliable Supply for GMP Manufacturing.