4-tert-Butylphenylboronic Acid

• Appearance: White to off-white crystalline powder

• Assay (HPLC): ≥ 99.0%

• Melting Point: 188 - 193°C

• Loss on Drying: ≤ 0.5%

• Solubility: Soluble in Methanol, Ethanol, DMSO; Insoluble in Water.

• Storage: Keep cold (2-8°C recommended) and dry to prevent anhydride formation.

A versatile organoboron building block widely used in:

• Suzuki-Miyaura Coupling: Acts as a robust aryl source to introduce the 4-tert-butylphenyl group into biaryl scaffolds.

• Pharmaceutical Synthesis: Intermediate for antibiotics (e.g., Tetracycline derivatives) and antifungal agents.

• Advanced Materials (OLED): Precursor for synthesizing hole-transporting materials and organic electroluminescent compounds due to its bulky tert-butyl group preventing aggregation.

• Biosensors: Used in the development of saccharide sensors (glucose sensing) via boronic acid-diol interactions.