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Diethyl Oxalate

CAS NO. 95-92-1
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  • Industrial Grade ≥99%

  • Royalchem

  • 95-92-1

Product Name Diethyl Oxalate
(Synonyms: Oxalic Acid Diethyl Ester; Ethyl Oxalate; Diethyl Ethanedioate)                
CAS NO. 95-92-1
Formula & Weight C6H10O(MW: 146.14) |  EC: 202-464-1 | MDL: MFCD00009119
Chemical Structure Diethyl Oxalate molecular structure CAS 95-92-1
Typical Specifications Typical industrial specification; batch COA prevails                
  • Appearance: Colorless transparent liquid

  • Purity: ≥ 99.0%

  • Water: ≤ 0.10%

  • Density: Approximately 1.076–1.08 g/mL

Physical Properties
  • Boiling Point: Approximately 184–186 °C

  • Melting Point: Approximately -41 °C

  • Flash Point: Approximately 75–76 °C

  • Refractive Index: Approximately 1.410

  • Solubility: Miscible with alcohol, acetone, ether and many common organic solvents; moisture sensitive and may decompose in contact with water.

Key Applications

Diethyl Oxalate is a versatile oxalate ester used primarily as an organic synthesis reagent and chemical intermediate.

  • Pharmaceutical & Fine Chemical Intermediates: Used as a building block and synthetic intermediate in pharmaceutical and specialty chemical manufacturing, particularly where oxalyl or carbonyl-containing structures are required.

  • Organic Synthesis: The two ester carbonyl groups enable condensation and oxalylation chemistry. Diethyl Oxalate is commonly used in Claisen-type reactions to prepare alpha-keto esters, dicarbonyl intermediates and precursors for heterocyclic compounds.

  • Dye Intermediates: Diethyl Oxalate has long been used as an intermediate and synthetic reagent in dye and specialty organic chemical manufacturing.

  • Specialty Solvent Applications: Reported uses include selected plastics, cellulose-derived materials, perfumes and other specialty organic systems where its ester solvency profile is suitable.

Packaging & Storage Packaging: Industrial packaging according to order quantity and dangerous-goods transportation requirements; final pack size and material are confirmed with the commercial quotation.
Storage: Keep containers tightly closed in a cool, dry and well-ventilated area, away from heat and incompatible materials.

Sourcing Diethyl Oxalate for Pharmaceutical, Dye or Organic Synthesis?

Royalchem supplies Diethyl Oxalate (CAS 95-92-1) with a typical industrial-grade purity of ≥99.0% for pharmaceutical intermediates, dye intermediates and fine-chemical synthesis. We support commercial sourcing with batch-specific COA, SDS, specification confirmation and international logistics coordination.        
Contact Royalchem for the latest specification, packaging information and bulk quotation.

Industrial Applications of Diethyl Oxalate

Organic Synthesis Diethyl Oxalate is a useful two-carbon oxalyl building block. Under suitable reaction conditions, it participates in condensation reactions with compounds containing active carbon centers, providing access to alpha-keto esters, dicarbonyl intermediates and precursors for heterocyclic synthesis.
Pharmaceutical & Fine Chemicals Diethyl Oxalate is widely referenced as an intermediate and synthetic reagent in pharmaceutical and specialty chemical manufacturing. Its reactive ester groups make it suitable for constructing carbonyl-rich intermediates used in multi-step synthesis.
Dye & Specialty Intermediates Industrial Diethyl Oxalate is also used in the manufacture of dye and specialty organic intermediates, where controlled purity and water content can be important for downstream reaction consistency.
Specialty Solvent Uses Diethyl Oxalate has also been reported as a solvent for selected plastics and specialty organic systems and in applications associated with perfumes and related fine chemicals.

Typical Quality Specifications

Test Item Typical Specification
Appearance Colorless transparent liquid
Assay, % ≥ 99.0
Water, % ≤ 0.10
Density, g/mL Approx. 1.076–1.08

Typical values only. Final specifications and analytical results are subject to the actual batch COA.

Packaging, Storage & Shipping

Packaging Commercial packaging is selected according to order quantity, product specification and dangerous-goods transport requirements. Final package size and container type are confirmed with the order.
Storage Keep containers tightly closed in a cool, dry and well-ventilated place. Protect from heat and incompatible materials and follow the storage conditions stated in the shipment SDS.
Documentation Batch COA, SDS, specification confirmation and logistics-related documentation can be provided according to the commercial shipment.

Frequently Asked Questions

What is Diethyl Oxalate mainly used for? Diethyl Oxalate is mainly used as an organic synthesis reagent and chemical intermediate. Major application areas include pharmaceutical intermediates, dye intermediates, condensation and oxalylation chemistry, and selected specialty solvent applications.
What are the CAS number, formula and molecular weight? Diethyl Oxalate has CAS number 95-92-1, molecular formula C6H10O4, molecular weight 146.14 and EC number 202-464-1.
Is Diethyl Oxalate readily biodegradable? Biodegradation models may predict that Diethyl Oxalate has biodegradation potential, but such predictions should not be treated as equivalent to a certified OECD ready-biodegradability test. Customers requiring environmental or sustainability claims should review the applicable regulatory or test documentation before use.
What is the difference between Diethyl Oxalate and Oxalyl Chloride? Both are derivatives of oxalic acid but have very different reactivity. Diethyl Oxalate is an ester commonly used in condensation and oxalylation chemistry, while Oxalyl Chloride is a much more reactive acid chloride widely used for converting carboxylic acids to acid chlorides and in reactions such as Swern oxidation.
Can Royalchem provide COA and SDS? Yes. Batch-specific COA, SDS and specification confirmation can be provided for commercial supply. Contact Royalchem to confirm the latest specification, available quantity, packaging and shipping requirements before ordering.

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